Santa Cruz Vacation Packages

We make it simple to travel the world, with Santa Cruz vacation packages starting from as little as . You'll have the flexibility to combine your favorite airlines, hotels and car rental. For the ultimate getaway, why not add a couple of tours and activities to your itinerary?

One of the easiest ways to save money (and time) is to bundle your bookings with Expedia. Hotels, rental cars, flights and activities — we've got them all covered. Pick a combination that best fits you and watch your savings pile up. Of course, a travel package is never a one-size-fits-all. That's why we offer more than 550 partner airlines and 1,000,000 properties across the world, which lets you customize your Santa Cruz adventure.

For properties in Samaipata with cozy beds and friendly service, look up Sun Hotel and Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel. If you're swinging by San Jose de Chiquitos as well, you'll get a great night's sleep at Camino Real Hotel or Marriott Santa Cruz de la Sierra Hotel.

It's hard to pick the best time for airfares, but we generally say the earlier, the better. Many international journeys on Expedia become available up to 12 months in advance. If you're booking late, don't stress. Discounted prices occasionally appear within a few weeks of departure dates.

Flights, car rentals and hotels — we connect you to the very best deals. All you'll have to do is figure out your favorite combination. After you've made your booking, you can add on the exciting stuff like activities and tours. Our travel packages make it simple to create an exciting Santa Cruz escape.

Bundling your bookings into a Santa Cruz vacation package is the most convenient way to organize your trip. Not only that, you'll save just for combining your hotels, flights and car rentals. Once you've booked, why not add on a day tour or an activity?

Yes — that's one of the best things about an Expedia package. You're in control. We have more than 550 airline partners throughout the world, so you have loads of choice when organizing your Santa Cruz getaway.

Yes you can, and we'll help you every step of the way. You may be able to change or cancel your Santa Cruz vacation package at no cost within 24 hours of booking. However, you may be charged a fee by your hotel, airline or car rental company if you booked more than 24 hours ago. If life throws you a curveball, browse our Customer Service Portal for more information.